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原发性胃肠道淋巴瘤的诊疗进展

Progress in Diagnosis and Treatment of Primary Gastrointestinal Lymphoma

临床医学前沿 / 2021,3(4)：84-99 / 2021-10-27 400 483

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• 作者： 田丰宇      于岩波     
• 单位：

  山东大学齐鲁医院消化内科，济南

• 关键词： 胃肠道；淋巴瘤；病理；诊断；临床表现；治疗
• Gastrointestinal tract; Lymphoma; Pathology; Diagnosis; Clinical feature; Treatment
• 摘要： 原发性胃肠道淋巴瘤（Primary Gastrointestinal Lymphomas，PGIL）是一种较为罕见的肿瘤亚型，占所有结外淋巴瘤的 5%-20%，其包括了弥漫性大细胞B淋巴瘤、黏膜相关淋巴组织淋巴瘤、原发性结外滤泡性淋巴瘤、套细胞淋巴瘤、Burkitt 淋巴瘤、肠道T 细胞淋巴瘤等多种淋巴瘤。PGIL 的发病率日益增高，随着影像诊断技术的不断进步，对于胃肠道淋巴瘤的诊疗逐步精确化。本篇综述了PGIL 各部位（胃、小肠、结直肠）常见病理类型，诊断方法、常见临床表现、治疗方法以及生存预后等因素。为临床医师对PGIL 的诊疗提供理论支持。
• Primary gastrointestinal lymphomas (PGIL) is a relatively rare tumor subtype, accounting for 5%-20% of all extra nodal lymphomas, including diffusion large B-cell lymphoma, Mucosa-associated lymphoid tissue lymphoma, mantle cell lymphoma, Burkitt lymphoma, follicular lymphoma, intestinal T cell lymphoma and other lymphomas. The incidence of PGIL is increasing day by day. With the continuous advancement of imaging diagnosis technology, the diagnosis and treatment of gastrointestinal lymphoma is gradually refined. This article reviewed the common pathological types, diagnostic methods, common clinical manifestations, treatment methods, survival prognosis and other factors of each part of PGIL (stomach, small intestine, colorectal). Provide theoretical support for clinicians in the diagnosis and treatment of PGIL.
• DOI： https://doi.org/10.35534/fcm.0304011
• 引用： 田丰宇，于岩波．原发性胃肠道淋巴瘤的诊疗进展［J］．临床医学前沿，2021，3（4）：84-99．