国际中文开源期刊平台

焦虑与压力感的生物指标：心率变异性相关性

Biomarkers of Anxiety and Stress: Correlation of Heart Rate Variability

临床医学前沿 / 2022,4(2)：53-62 / 2022-05-17 387 998

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• 作者： 帅军      陈晨      林铮      秦晓愚      王丽杰      张振华     
• 单位：

  海军陆战队医院，潮州
  

• 关键词： 新兵；焦虑；压力感；心率变异性
• Marine Corps recruits; Sense of pressure; Anxiety; Heart rate variability (HRV)
• 摘要： 目的：探索自主神经在焦虑情绪中的活动特点，对将 HRV 作为心理应激判断指标供参考依据。方法：对海军陆战队 2021 年新兵进行心理健康状况评估，对其中焦虑者的压力感、焦虑与心率变异性进行研究。采用汉密顿焦虑量表（HAMA）、项目组编制“压力感自我评价问卷”以及 HRV 测定进行相关分析。结果：被试 均为焦虑状态，HAMA 总分 >14 分（100%），平均值 23.18±4.13，躯体性焦虑因子分 11.45±3.14，精神性焦虑因子分 10.28±2.39。责任重（t=18.84，P<0.001）、受周围负性事件影（t=12.089，P<0.001）和训练超负荷（t=14.187，P<0.001）为压力感来源中的主要因素。HRV 时域SDNN、SDANN、RMSS与PNN50均低于参考值（t=-8.28，-5.44，-15.77，-7.42，p<0.05）；焦虑 者的LF,HF与参考值间无明显差异（t=1.03，-1.21，p>0.05），LF/HF 明显高于参考值（t=4.49，p<0.05）。HAMA总分与SDNN呈负相关（r=-0.53，p<0.05），躯体性焦虑因子分与LF呈正相关（r=0.54，p<0.05），精神性焦虑 因子分与PNN50呈负相关（r=-0.60，p<0.05）。结论：焦虑者静息状态下交感神经功能亢进，迷走神经功能降低，其功能失调与焦虑有关。
• Objective: To explore the characteristics of autonomic nerve activity in anxiety, and to provide reference for HRV as an indicator of psychological stress. Methods: The mental health status of Marine Corps recruits in 2021 was assessed, and the stress, anxiety and heart rate variability of anxious recruits were studied. Hamilton Anxiety Scale (HAMA), “Pressure self-assessment Questionnaire” prepared by the project team and HRV measurement were used for correlation analysis. Results: All subjects were in anxiety state, HAMA total score>14 (100%), average 23.18±4.13, somatic anxiety factor score 11.45±3.14, mental anxiety factor score 10.28±2.39. Heavy duty (t=18.84, P<0.001), affected by the surrounding negative events (t=12.089, P<0.001) and training overload (t=14.187, P<0.001) was the main factor in the source of pressure feeling. HRV time domain SDNN, SDANN, RMSS and PNN50 are all lower than the reference value (t=-8.28, -5.44, -15.77, -7.42, p<0.05); There was no significant difference between LF and HF of anxious personnel and the reference value (t=1.03, -1.21, p>0.05), and LF/HF was significantly higher than the reference value (t=4.49, p<0.05). HAMA scores were negatively correlated with SDNN (r=-0.53, p<0.05), somatic anxiety factor score was positively correlated with LF (r=0.54, p<0.05), the score of mental anxiety factor was negatively correlated with PNN50 (r=-0.60, p<0.05). Conclusion: The hyperactivity of sympathetic nerve and the decrease of vagus nerve in anxious personnel are related to anxiety.
• DOI： https://doi.org/10.35534/fcm.0402006
• 引用： 帅军，陈晨，林铮，等．焦虑与压力感的生物指标：心率变异性相关性［J］．临床医学前沿，2022，4（2）：53-62．