Abstract:
Objective: to investigate the clinical features and treatment of islet cell
tumor. Methods: the clinical manifestations, examination methods and treatment
results of 12 cases of islet cell tumor admitted to our hospital from 2014 to 2018 were
retrospectively analyzed. Results: 11 cases of insulinoma and 1 case of malignant non-
functional islet cell tumor were confirmed by surgery and pathology. Tumor location: 1
case of pancreatic head, 3 cases of pancreatic neck, 4 cases of pancreatic body, 4 cases of
pancreatic body and tail junction, 2 cases of pancreatic tail. All 12 patients underwent
surgical treatment, including 5 patients who underwent pancreaticotailectomy and 7
patients who underwent local tumor resection. Postoperatively, the blood glucose of
patients with functional islet cell tumor increased to 5.5-11 mmol/L, and the symptoms
of abdominal pain of patients with non-functional islet cell tumor disappeared. All 12
cases were cured and discharged from hospital without death. Conclusion: islet cell
tumor is mainly insulinoma and nonfunctional islet cell tumor.
目的:探讨胰岛细胞瘤的临床特征、治疗方法。方法:对我院 2014 年
到 2018 年收治的 12 例胰岛细胞瘤的临床表现、检查方法和治疗结果进行回顾
分析。结果:本组经手术切除病理证实胰岛素瘤 11 例,恶性非功能性胰岛细胞
瘤 1 例。肿瘤位置:胰头 1 例,胰颈 3 例,胰体 4 例,胰体尾交界处 4 例,胰
尾 2 例。12 例均施行手术治疗,行胰体尾切除术 5 例,肿瘤局部切除术 7 例。
功能性胰岛细胞瘤术后血糖上升为 5.5 ~ 11mmol/L,非功能性胰岛细胞瘤患者
术后腹痛症状消失。12 例均治愈出院,无手术死亡。结论:胰岛细胞瘤主要是
胰岛素瘤和无功能胰岛细胞瘤,可行单纯肿瘤切除或胰腺部分切除。