As China begins to enter a new stage of development, the digital economy has gradually become an important force to promote the high-level development of the Chinese economy and expand its trade competitiveness. Even under the new world development pattern with increasing instability, the development momentum of the digital economy still remains strong. At the same time, the integration of the digital economy and various industries is also in full swing. As the lifeblood of national economic growth, manufacturing industry plays an important role in supporting other industries. Among them, the “high-end manufacturing industry” is not only the basic industry, but also the core industry. China’s “Made in China 2025” plan also points out the key role of high-end manufacturing. Although China is already a major manufacturing country, it still lags behind developed countries in terms of key core technology breakthroughs and advanced modern equipment manufacturing, resulting in China’s high-end manufacturing industry being locked at the low end of the value chain. Therefore, the influence of digital economy development for high-end manufacturing global value chain status, help from a new perspective of the process of industry upgrading transformation, the new form of economic development and traditional industry innovation and development of effective cohesion, speed up the digital transformation of high-end manufacturing in China, improve the export competitiveness of high-end manufacturing in China. This paper uses Stata software to empirically explore the impact of the development level of digital economy on the export trade of high-end manufacturing industry, and puts forward relevant suggestions.